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Dear Editor: Pegylation is an important technique that has greatly improved the pharmacologic profile of interferon. Compared with conventional interferon(IFN)-a injections, pegylated interferon (PEG-IFN) has a longer half-life allowing for once-weekly injections and superior antiviral efficacy in the treatment of hepatitis C when used in combination with ribavirin. However, cutaneous side effects had been reported more frequent with PEG-IFN. We present a patient with chronic hepatitis C (CHC) in whom PEG-IFN, but not conventional interferon therapy induced severe skin lesions at the sites of injection.

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2012-06-14   |   746 visitas   |   Evalua este artículo 0 valoraciones

Vol. 11 Núm.4. Julio-Agosto 2012 Pags. 570-571 Ann Hepatol 2012; 11(4)